• Molecular NameLipoic Acid
  • Synonym1,2-Dithiolane-3R-pentanoic acid; alpha-Lipoic acid; Lipoate; Thioctic acid
  • Weight206.33
  • Drugbank_IDDB00166
  • ACS_NO1200-22-2
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.93
  • pkaN/A
  • LogD (pH=7, predicted)0.8
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.75
  • LogSw (predicted, AB/LogsW2.0)0.49
  • Sw (mg/ml) (predicted, ACD/Labs)0.24
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA87.9
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyALA has been used for the treatment of various cancers for which no effective treatments exist.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability29.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A