- Molecular NameLevamisole
- Synonymdl-Tetramisol; dl-Tetramisole; L-Tetramisole; Levamisol [INN-Spanish]; Levamisole hydrochloride; Levamisolum [INN-Latin]; Phenyl imidothiazole
- Weight204.297
- Drugbank_IDDB00848
- ACS_NO14769-73-4
- Show 2D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)2.15
- pka8.0
- LogD (pH=7, predicted)1.11
- Solubility (experiment)210 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-0.97
- LogSw (predicted, AB/LogsW2.0)0.08
- Sw (mg/ml) (predicted, ACD/Labs)0.31
- No.of HBond Donors0
- No.of HBond Acceptors2
- No.of Rotatable Bonds1
- TPSA40.9
- StatusFDA approved
- AdministrationN/A
- PharmacologyAn antibiotic belonging to a class of synthetic imidazothiazole derivatives.
- Absorption_value95.0
- Absorption (description)Levamisole is readily absorbed after oral administration
- Caco_2N/A
- Bioavailability65.0
- Protein binding22.5
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmExtensively metabolised.
- Half life4 h
- ExcretionIt is almost completely excreted in the urine and faeces within 48 h.
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)LD50=180 mg/kg
- LD50 (mouse)N/A