• Molecular NameThiabendazole
  • SynonymTBDZ; TBZ; Thiabendazol; Thiabendole; Thiabenzazole; Thiabenzole; Tiabendazol; Tiabendazole
  • Weight201.253
  • Drugbank_IDDB00730
  • ACS_NO148-79-8
  • Show 2D model
  • LogP (experiment)2.47
  • LogP (predicted, AB/LogP v2.0)2.42
  • pka4.64
  • LogD (pH=7, predicted)2.42
  • Solubility (experiment)0.028 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-3.53
  • LogSw (predicted, AB/LogsW2.0)0.1
  • Sw (mg/ml) (predicted, ACD/Labs)0.06
  • No.of HBond Donors1
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds1
  • TPSA69.81
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA fungicide and parasiticide.
  • Absorption_value90.0
  • Absorption (description)Rapidly absorbed and peak plasma concentration is reached within 1 to 2 hours after the oral administration of a suspension. Some systemic absorption may occur from topical preparations applied to the skin.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic. Metabolized almost completely to the 5-hydroxy form which appears in the urine as glucuronide or sulfate conjugates.
  • Half life8 h
  • Excretion90% Urine; 5% Faeces
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityOverdosage may be associated with transient disturbances of vision and psychic alterations.
  • LD50 (rat)LD50=3.1 g/kg
  • LD50 (mouse)LD50=3.6 g/kg