• Molecular NameMetharbital
  • SynonymNA
  • Weight198.222
  • Drugbank_IDDB00463
  • ACS_NO50-11-3
  • Show 2D model
  • LogP (experiment)1.15
  • LogP (predicted, AB/LogP v2.0)1.25
  • pka8.3
  • LogD (pH=7, predicted)1.22
  • Solubility (experiment)1.98 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.27
  • LogSw (predicted, AB/LogsW2.0)4.81
  • Sw (mg/ml) (predicted, ACD/Labs)10.22
  • No.of HBond Donors1
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds2
  • TPSA66.48
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySigns of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=820