• Molecular NameIsoflurane
  • SynonymNA
  • Weight184.491
  • Drugbank_IDDB00753
  • ACS_NO26675-46-7
  • Show 3D model
  • LogP (experiment)2.06
  • LogP (predicted, AB/LogP v2.0)1.92
  • pkaN/A
  • LogD (pH=7, predicted)1.92
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-1.58
  • LogSw (predicted, AB/LogsW2.0)2.18
  • Sw (mg/ml) (predicted, ACD/Labs)4.89
  • No.of HBond Donors0
  • No.of HBond Acceptors1
  • No.of Rotatable Bonds3
  • TPSA9.23
  • StatusFDA approved
  • Administrationinhalation
  • PharmacologyA halogenated ether used for inhalational anesthesia. Together with enflurane and halothane, it replaced the flammable ethers used in the pioneer days of surgery. Its use in human medicine is now starting to decline, being replaced with sevoflurane, desflurane and the intravenous anaesthetic propofol. Isoflurane is still frequently used for veterinary anaesthesia.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmNot extensive and minimal
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A