• Molecular NameAscorbic acid
  • SynonymAA; Ascorbate; Vitamin C; L-Ascorbate; L-Ascorbic Acid; L-Lyxoascorbic Acid; L-Xyloascorbic Acid
  • Weight176.124
  • Drugbank_IDN/A
  • ACS_NO50-81-7
  • Show 2D model
  • LogP (experiment)-1.64
  • LogP (predicted, AB/LogP v2.0)-2.05
  • pka4.17, 11.6
  • LogD (pH=7, predicted)-4.83
  • Solubility (experiment)333 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)0.75
  • LogSw (predicted, AB/LogsW2.0)879.4
  • Sw (mg/ml) (predicted, ACD/Labs)532.52
  • No.of HBond Donors4
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds2
  • TPSA107.22
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA sugar acid with antioxidant properties.
  • Absorption_valueN/A
  • Absorption (description)35
  • Caco_2N/A
  • Bioavailability80.0
  • Protein binding25.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolized to inactive compounds including ascorbic acid-2-sulfate and oxalic acid.
  • Half life16 days (3.4 hours in people who have excess levels of vitamin C)
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityLD50: 11.9 g/kg (oral, rat)
  • LD50 (rat)N/A
  • LD50 (mouse)N/A