• Molecular NamePyridoxine
  • SynonymAdermin hydrochloride; Adermine hydrochloride; Aderomine hydrochloride; Hexabione hydrochloride; PN; Pyridoxin hydrochloride; Pyridoxine Chloride; Pyridoxine HCl; Pyridoxine hydrochloride; Pyridoxine hydrogen chloride; Pyridoxinium Chloride; Pyridoxinum Hydrochloricum; Pyridoxol hydrochloride; Vitamin B6
  • Weight169.18
  • Drugbank_IDDB00165
  • ACS_NO65-23-6
  • Show 3D model
  • LogP (experiment)-0.72
  • LogP (predicted, AB/LogP v2.0)-0.53
  • pka5.0 (CN), 9.0 (COH)
  • LogD (pH=7, predicted)-0.83
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.65
  • LogSw (predicted, AB/LogsW2.0)990.75
  • Sw (mg/ml) (predicted, ACD/Labs)37.95
  • No.of HBond Donors3
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds2
  • TPSA73.58
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyOne of the compounds that can be called vitamin B6, along with pyridoxal and pyridoxamine. It differs from pyridoxamine by the substituent at the '4' position. It is often used as 'pyridoxine hydrochloride'.
  • Absorption_valueN/A
  • Absorption (description)The B vitamins are readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Pyridoxine is absorbed mainly in the jejunum.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding0.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic.
  • Half life15~20 days
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityToxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.
  • LD50 (rat)LD50=4 gm/kg
  • LD50 (mouse)N/A