- Molecular NameNystatin
- SynonymNA
- Weight926.107
- Drugbank_IDDB00646
- ACS_NO1400-61-9
- Show 2D model
- LogP (experiment)-0.534
- LogP (predicted, AB/LogP v2.0)0.19
- pkaN/A
- LogD (pH=7, predicted)-2.32
- Solubility (experiment)0.36 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-4.33
- LogSw (predicted, AB/LogsW2.0)0.73
- Sw (mg/ml) (predicted, ACD/Labs)0.04
- No.of HBond Donors13
- No.of HBond Acceptors18
- No.of Rotatable Bonds3
- TPSA319.61
- StatusFDA approved
- AdministrationTopical & oral (but not absorbed)
- PharmacologyA polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida spp.
- Absorption_valueN/A
- Absorption (description)Gastrointestinal absorption of nystatin is insignificant. Most orally administered nystatin is passed unchanged in the stool.
- Caco_2N/A
- Bioavailability1.0
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmN/A
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A