• Molecular NameVindesine
  • SynonymDesacetylvinblastine Amide Sulfate; Vindesine Sulfate
  • Weight753.941
  • Drugbank_IDDB00309
  • ACS_NO59917-39-4
  • Show 2D model
  • LogP (experiment)4.4
  • LogP (predicted, AB/LogP v2.0)2.48
  • pka6.0, 7.7
  • LogD (pH=7, predicted)1.91
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.29
  • LogSw (predicted, AB/LogsW2.0)3.18
  • Sw (mg/ml) (predicted, ACD/Labs)0.04
  • No.of HBond Donors6
  • No.of HBond Acceptors12
  • No.of Rotatable Bonds7
  • TPSA164.82
  • StatusFDA approved
  • AdministrationIntravenous
  • PharmacologyAn anti-mitotic vinca alkaloid used in chemotherapy. It is used to treat many different types of cancer, including leukaemia, lymphoma, melanoma, breast cancer, and lung cancer.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding70.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (CYP3A4-mediated)
  • Half life24 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A