• Molecular NameNatamycin
  • SynonymNA
  • Weight665.733
  • Drugbank_IDDB00826
  • ACS_NO7681-93-8
  • Show 3D model
  • LogP (experiment)0.495
  • LogP (predicted, AB/LogP v2.0)-0.7
  • pkaN/A
  • LogD (pH=7, predicted)-3.2
  • Solubility (experiment)0.41 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-3.61
  • LogSw (predicted, AB/LogsW2.0)1.58
  • Sw (mg/ml) (predicted, ACD/Labs)0.15
  • No.of HBond Donors8
  • No.of HBond Acceptors14
  • No.of Rotatable Bonds3
  • TPSA240.22
  • StatusFDA approved
  • AdministrationTopical
  • PharmacologyNatamycin is used to treat fungal infections, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. It is applied as a cream, in eyedrops, or (for oral infections) in a lozenge.
  • Absorption_valueN/A
  • Absorption (description)Systemic absorption should not be expected following topical administration, and as with other polyene antibiotics, absorption from the gastrointestinal tract is very poor.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A