• Molecular NameRemikiren
  • SynonymRo 42-5892
  • Weight630.851
  • Drugbank_IDDB00212
  • ACS_NO126222-34-2
  • Show 2D model
  • LogP (experiment)2.75
  • LogP (predicted, AB/LogP v2.0)2.77
  • pkaN/A
  • LogD (pH=7, predicted)2.4
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-5.5
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors5
  • No.of HBond Acceptors10
  • No.of Rotatable Bonds16
  • TPSA169.86
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA renin inhibitor under development for the treatment of hypertension (high blood pressure).
  • Absorption_valueN/A
  • Absorption (description)Absorbed following oral administration.
  • Caco_2N/A
  • Bioavailability1.0
  • Protein binding83.0
  • Volume of distribution (VD)70L
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A