• Molecular NameParomomycin
  • SynonymAminosidin; Aminosidine; Paramomycin sulfate; paromomycin
  • Weight615.634
  • Drugbank_IDDB01421
  • ACS_NO1263-89-4
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-10.28
  • pkaN/A
  • LogD (pH=7, predicted)-14.0
  • Solubility (experiment)Soluble
  • LogS (predicted, ACD/Labs)(ph=7)0.21
  • LogSw (predicted, AB/LogsW2.0)2096.99
  • Sw (mg/ml) (predicted, ACD/Labs)1000.0
  • No.of HBond Donors18
  • No.of HBond Acceptors19
  • No.of Rotatable Bonds9
  • TPSA347.32
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn aminoglycoside antibiotic
  • Absorption_value0.0
  • Absorption (description)Neomycin E is poorly absorbed after oral administration, with almost 100% of the drug recoverable in the stool.
  • Caco_2N/A
  • Bioavailability0.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionFecal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityNausea, abdominal cramps, and diarrhea have been reported in patients on doses over 3 g daily.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A