• Molecular NameHeparin
  • SynonymAlpha-Heparin ; heparin ; Heparin sodium ; Heparin sodium preservative Free ; Heparin sodium salt ; Heparin sulfate; Heparinate ; Heparinic acid ; Sodium heparin
  • Weight1134.93
  • Drugbank_IDDB01109
  • ACS_NO9005-49-6
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)N/A
  • pkaN/A
  • LogD (pH=7, predicted)N/A
  • Solubility (experiment)Soluble
  • LogS (predicted, ACD/Labs)(ph=7)N/A
  • LogSw (predicted, AB/LogsW2.0)N/A
  • Sw (mg/ml) (predicted, ACD/Labs)N/A
  • No.of HBond DonorsN/A
  • No.of HBond AcceptorsN/A
  • No.of Rotatable BondsN/A
  • TPSAN/A
  • StatusFDA approved
  • AdministrationIV, SC
  • PharmacologyA highly-sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
  • Absorption_valueN/A
  • Absorption (description)Well absorbed following subcutaneous administration, with a mean bioavailability of 92% (based on anti-factor Xa activity).
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)0.058 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • Metabollsmhepatic
  • Half life1.5 h
  • ExcretionN/A
  • Urinary ExcretionNegligible
  • CleranceN/A
  • ToxicitySymptoms of overdose may include excessive bleeding and bruising.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A