• Molecular NameStreptomycin
  • SynonymStreptomycin a Sulfate; Streptomycin Sesquisulfate Hydrate; Streptomycin Sulfate; Streptomycin Sulphate; Streptomycin, Sulfate Salt
  • Weight581.58
  • Drugbank_IDDB01082
  • ACS_NO57-92-1
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-7.24
  • pkaN/A
  • LogD (pH=7, predicted)-12.65
  • Solubility (experiment)Soluble
  • LogS (predicted, ACD/Labs)(ph=7)0.24
  • LogSw (predicted, AB/LogsW2.0)18675.9
  • Sw (mg/ml) (predicted, ACD/Labs)74.82
  • No.of HBond Donors16
  • No.of HBond Acceptors19
  • No.of Rotatable Bonds11
  • TPSA331.43
  • StatusFDA approved
  • AdministrationIntramuscular, intravenous
  • PharmacologyAn antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis.
  • Absorption_value1.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability1.0
  • Protein binding25.0
  • Volume of distribution (VD)0.24 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life2~4 h, increased in neonates, in elderly subjects, and in renal impairment.
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySide effect include nausea, vomiting, and vertigo, paresthesia of face, rash, fever, urticaria, angioneurotic edema, and eosinophilia.
  • LD50 (rat)LD50=430 mg/kg (Orally in rats with Streptomycin Sulfate)
  • LD50 (mouse)N/A