• Molecular NameCefotetan
  • SynonymCefotetanum [inn-latin]
  • Weight575.628
  • Drugbank_IDDB01330
  • ACS_NO69712-56-7
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-2.35
  • pkaN/A
  • LogD (pH=7, predicted)-7.35
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.7
  • LogSw (predicted, AB/LogsW2.0)0.99
  • Sw (mg/ml) (predicted, ACD/Labs)0.1
  • No.of HBond Donors5
  • No.of HBond Acceptors15
  • No.of Rotatable Bonds9
  • TPSA321.13
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often grouped together with second-generation cephalosporins and has a similar antibacterial spectrum, but with additional anti-anaerobe converage.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding85.0
  • Volume of distribution (VD)0.14 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life3.6 h
  • ExcretionN/A
  • Urinary Excretion67
  • Clerance0.23CLcr + 0.14 ml/min/kg
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A