• Molecular NameGliquidone
  • SynonymNA
  • Weight527.642
  • Drugbank_IDDB01251
  • ACS_NO33342-05-1
  • Show 3D model
  • LogP (experiment)4.6
  • LogP (predicted, AB/LogP v2.0)4.42
  • pkaN/A
  • LogD (pH=7, predicted)2.61
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.48
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.01
  • No.of HBond Donors2
  • No.of HBond Acceptors9
  • No.of Rotatable Bonds7
  • TPSA130.26
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2.
  • Absorption_value95.0
  • Absorption (description)Readily absorbed after oral administration.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding99.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)Plasma:whole blood ratio, about 1.9.
  • MetabollsmExtensively metabolised by hydroxylation and demethylation to inactive metabolites.
  • Half life1.5 h
  • ExcretionLess than 5% of a dose is excreted in the urine and about 95% is eliminated in the faeces, via the bile.
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A