• Molecular NamePiperacillin
  • SynonymPiperacillin Anhydrous
  • Weight517.563
  • Drugbank_IDDB00319
  • ACS_NO61477-96-1
  • Show 3D model
  • LogP (experiment)0.5
  • LogP (predicted, AB/LogP v2.0)0.75
  • pkaN/A
  • LogD (pH=7, predicted)-3.22
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.2
  • LogSw (predicted, AB/LogsW2.0)2.96
  • Sw (mg/ml) (predicted, ACD/Labs)0.12
  • No.of HBond Donors3
  • No.of HBond Acceptors12
  • No.of Rotatable Bonds6
  • TPSA181.73
  • StatusFDA approved
  • AdministrationIV, IM
  • PharmacologyAn extended spectrum beta-lactam antibiotic of the ureidopenicillin class. It is normally used together with a beta-lactamase inhibitor such as tazobactam
  • Absorption_value0.0
  • Absorption (description)Piperacillin is not absorbed orally, and rapidly absorbed following intramuscular injection.
  • Caco_2N/A
  • Bioavailability0.0
  • Protein binding20.0
  • Volume of distribution (VD)0.15~0.21 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmLargely not metabolised
  • Half life36~72 min
  • Excretion20% in bile, 80% unchanged in urine
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A