• Molecular NameCandoxatril
  • SynonymNA
  • Weight515.647
  • Drugbank_IDDB00616
  • ACS_NON/A
  • Show 3D model
  • LogP (experiment)4.874
  • LogP (predicted, AB/LogP v2.0)4.92
  • pkaN/A
  • LogD (pH=7, predicted)2.69
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.72
  • LogSw (predicted, AB/LogsW2.0)0.02
  • Sw (mg/ml) (predicted, ACD/Labs)0.01
  • No.of HBond Donors2
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds13
  • TPSA111.16
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyN/A
  • Absorption_valueN/A
  • Absorption (description)Systemic availability of candoxatrilat from the oral prodrug, candoxatril, was estimated to be 88, 53, 42, 17 and 32% in mouse, rat, rabbit, dog and man respectively
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A