- Molecular NameCefmenoxime
- SynonymCefmenoxima [INN-Spanish]; Cefmenoxime hydrochloride; Cefmenoximum [INN-Latin]
- Weight511.568
- Drugbank_IDDB00267
- ACS_NO65085-01-0
- Show 3D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)-0.42
- pkaN/A
- LogD (pH=7, predicted)-4.4
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)-1.91
- LogSw (predicted, AB/LogsW2.0)2.85
- Sw (mg/ml) (predicted, ACD/Labs)0.04
- No.of HBond Donors4
- No.of HBond Acceptors14
- No.of Rotatable Bonds8
- TPSA269.65
- StatusFDA approved
- AdministrationIntramuscular, intravenous
- PharmacologyA third-generation cephalosporin antibiotic.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- BioavailabilityN/A
- Protein binding60.0
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmNegligible
- Half life1 h
- ExcretionRenal, unchanged
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityInformation on cefmenoxime overdosage in humans is not available. However, with other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
- LD50 (rat)N/A
- LD50 (mouse)N/A