• Molecular NameArgatroban
  • Synonymargatroban
  • Weight508.644
  • Drugbank_IDDB00278
  • ACS_NO74863-84-6
  • Show 2D model
  • LogP (experiment)0.749
  • LogP (predicted, AB/LogP v2.0)0.99
  • pkaN/A
  • LogD (pH=7, predicted)-1.52
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.52
  • LogSw (predicted, AB/LogsW2.0)10.36
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors7
  • No.of HBond Acceptors11
  • No.of Rotatable Bonds10
  • TPSA186.09
  • StatusFDA approved
  • Administrationintravenous
  • PharmacologyAn anticoagulant that is a small molecule direct thrombin inhibitor.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding54.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • Metabollsmhepatic
  • Half life39 and 51 min
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A