• Molecular NamePrednicarbate
  • SynonymNA
  • Weight488.577
  • Drugbank_IDDB01130
  • ACS_NO73771-04-7
  • Show 3D model
  • LogP (experiment)3.392
  • LogP (predicted, AB/LogP v2.0)3.01
  • pkaN/A
  • LogD (pH=7, predicted)3.01
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-5.67
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors1
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds9
  • TPSA116.2
  • StatusFDA approved
  • AdministrationTopical
  • PharmacologyA relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly.
  • Absorption_valueN/A
  • Absorption (description)Absorbed systemically across the stratum corneum.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPrimarily in skin
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A