• Molecular NameNicergoline
  • SynonymNA
  • Weight484.394
  • Drugbank_IDDB00699
  • ACS_NO27848-84-6
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)4.5
  • pkaN/A
  • LogD (pH=7, predicted)4.16
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.38
  • LogSw (predicted, AB/LogsW2.0)0.04
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors0
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds5
  • TPSA56.59
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn ergoloid mesylate derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability5.0
  • Protein binding84.5
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionVia urine (80%), via faeces (20%).
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A