• Molecular NamePranlukast
  • SynonymONO-RS 411
  • Weight481.512
  • Drugbank_IDDB01411
  • ACS_NO103177-37-3
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.53
  • pkaN/A
  • LogD (pH=7, predicted)0.38
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.51
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors2
  • No.of HBond Acceptors9
  • No.of Rotatable Bonds9
  • TPSA119.09
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA cysteinyl leukotriene receptor-1 antagonist.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding99.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (mainly CYP3A4)
  • Half life1.5 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A