• Molecular NameMibefradil
  • SynonymNA
  • Weight479.64
  • Drugbank_IDN/A
  • ACS_NO116644-53-2
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)5.6
  • pka4.8; 5.5
  • LogD (pH=7, predicted)3.84
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.04
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors1
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds11
  • TPSA58.22
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers.
  • Absorption_value69.0
  • Absorption (description)N/A
  • Caco_2-4.87
  • Bioavailability75.0
  • Protein binding99.0
  • Volume of distribution (VD)Steady state, 176 to 255 L; also reported as 3.5 to 5.7 L/kg.
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life17 to 25 h.
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A