• Molecular NameAlmitrine
  • SynonymAlmitrine bismesylate; Almitrine dimesylate; Almitrine mesylate
  • Weight477.563
  • Drugbank_IDDB00437
  • ACS_NO27469-53-0
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)5.1
  • pkaN/A
  • LogD (pH=7, predicted)5.09
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.66
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.01
  • No.of HBond Donors2
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds10
  • TPSA69.21
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA piperazine classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease.
  • Absorption_value90.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability63.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A