• Molecular NameCefmetazole
  • SynonymCefmetazole sodium; Cefmetazolo [INN-Spanish]; Cefmetazolum [INN-Latin]
  • Weight471.543
  • Drugbank_IDDB00274
  • ACS_NO56796-20-4
  • Show 3D model
  • LogP (experiment)-0.6
  • LogP (predicted, AB/LogP v2.0)-0.75
  • pkaN/A
  • LogD (pH=7, predicted)-4.72
  • Solubility (experiment)0.0942 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.6
  • LogSw (predicted, AB/LogsW2.0)5.67
  • Sw (mg/ml) (predicted, ACD/Labs)0.06
  • No.of HBond Donors2
  • No.of HBond Acceptors12
  • No.of Rotatable Bonds10
  • TPSA239.23
  • StatusFDA approved
  • Administrationintramuscular injection
  • PharmacologyA cephalosporin antibiotic, usually grouped with the second-generation cephalosporins.
  • Absorption_value10.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding70.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life1.50 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityWith other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
  • LD50 (rat) 3,204 mg/kg.
  • LD50 (mouse)N/A