• Molecular NamePivampicillin
  • SynonymAmpicillin pivaloyloxymethyl ester; Pivaloylampicillin; Pivaloyloxymethyl ampicillinate; Pivampicilina [inn-spanish]; Pivampicilline [inn-french]; Pivampicillinum [inn-latin]
  • Weight463.555
  • Drugbank_IDDB01604
  • ACS_NO33817-20-8
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)1.6
  • pka7.0
  • LogD (pH=7, predicted)1.13
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.35
  • LogSw (predicted, AB/LogsW2.0)1.28
  • Sw (mg/ml) (predicted, ACD/Labs)0.14
  • No.of HBond Donors3
  • No.of HBond Acceptors9
  • No.of Rotatable Bonds9
  • TPSA153.33
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA pivaloyloxymethylester of ampicillin. It is a prodrug, which is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability30.9
  • Protein binding20.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionRenal (76%)
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A