• Molecular NameCefamandole
  • SynonymCefadole; Cefamandole nafate
  • Weight462.511
  • Drugbank_IDDB01326
  • ACS_NO34444-01-4
  • Show 3D model
  • LogP (experiment)0.5
  • LogP (predicted, AB/LogP v2.0)-0.02
  • pkaN/A
  • LogD (pH=7, predicted)-3.95
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.32
  • LogSw (predicted, AB/LogsW2.0)23.23
  • Sw (mg/ml) (predicted, ACD/Labs)0.08
  • No.of HBond Donors3
  • No.of HBond Acceptors11
  • No.of Rotatable Bonds7
  • TPSA201.14
  • StatusFDA approved
  • AdministrationIntramuscular, intravenous
  • PharmacologyA second-generation broad-spectrum cephalosporin antibiotic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding74.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life0.8 h
  • ExcretionMostly renal, as unchanged drug
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A