• Molecular NameMinocycline
  • Synonymminocycline
  • Weight457.483
  • Drugbank_IDDB01017
  • ACS_NO10118-90-8
  • Show 3D model
  • LogP (experiment)0.05
  • LogP (predicted, AB/LogP v2.0)0.1
  • pka2.8, 5.0, 7.8, 9.5
  • LogD (pH=7, predicted)-2.58
  • Solubility (experiment)52 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-2.58
  • LogSw (predicted, AB/LogsW2.0)1.33
  • Sw (mg/ml) (predicted, ACD/Labs)0.97
  • No.of HBond Donors6
  • No.of HBond Acceptors10
  • No.of Rotatable Bonds3
  • TPSA164.63
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA broad spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability97.0
  • Protein binding76.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life11~22 h
  • Excretionmostly fecal, rest renal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)LD50=2380 mg/kg
  • LD50 (mouse)LD50=3600 mg/kg