- Molecular NamePimozide
- SynonymPimozida [INN-Spanish]; Pimozidum [INN-Latin]
- Weight447.529
- Drugbank_IDDB01100
- ACS_NO2062-78-4
- Show 2D model
- LogP (experiment)6.3
- LogP (predicted, AB/LogP v2.0)5.36
- pka7.3
- LogD (pH=7, predicted)4.3
- Solubility (experiment)0.01 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-4.81
- LogSw (predicted, AB/LogsW2.0)0.0
- Sw (mg/ml) (predicted, ACD/Labs)0.0
- No.of HBond Donors1
- No.of HBond Acceptors4
- No.of Rotatable Bonds6
- TPSA35.58
- StatusFDA approved
- AdministrationN/A
- PharmacologyAn antipsychotic drug.
- Absorption_value70.0
- Absorption (description)N/A
- Caco_2N/A
- Bioavailability40.0
- Protein binding99.0
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmHepatic, by cytochrome P450, isoenzymes 3A, and 1A2; metabolites are inactive
- Half life2 days
- Excretionurine, and to a lesser extent in feces
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)LD50=1100 mg/kg
- LD50 (mouse)LD50=228 mg/kg