• Molecular NameTirofiban
  • SynonymNA
  • Weight440.605
  • Drugbank_IDDB00775
  • ACS_NO144494-65-5
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.0
  • pkaN/A
  • LogD (pH=7, predicted)-0.5
  • Solubility (experiment)Very slightly soluble
  • LogS (predicted, ACD/Labs)(ph=7)-5.03
  • LogSw (predicted, AB/LogsW2.0)0.47
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors3
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds14
  • TPSA113.11
  • StatusFDA approved
  • AdministrationExclusively intravenous
  • PharmacologyAn antiplatelet drug.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability0.0
  • Protein binding65.0
  • Volume of distribution (VD)0.3~0.7 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmMetabolism appears to be limited.
  • Half life1.2~2.0 h
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityThe most common drug-related adverse event is bleeding.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A