• Molecular NamePolythiazide
  • SynonymNA
  • Weight439.887
  • Drugbank_IDDB01324
  • ACS_NO346-18-9
  • Show 2D model
  • LogP (experiment)1.58
  • LogP (predicted, AB/LogP v2.0)1.71
  • pkaN/A
  • LogD (pH=7, predicted)1.71
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.36
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.19
  • No.of HBond Donors3
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds5
  • TPSA151.63
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA thiazide diuretic.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding82.5
  • Volume of distribution (VD)4 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life26 h
  • Excretion25% of the drug was excreted unchanged in the urine
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A