• Molecular NamePivmecillinam
  • SynonymAmdinocillin pivoxil; Pivmecilinamo [inn-spanish]; Pivmecillinamum [inn-latin]
  • Weight439.577
  • Drugbank_IDDB01605
  • ACS_NO32886-97-8
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.53
  • pkaN/A
  • LogD (pH=7, predicted)1.9
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.49
  • LogSw (predicted, AB/LogsW2.0)0.29
  • Sw (mg/ml) (predicted, ACD/Labs)0.01
  • No.of HBond Donors0
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds8
  • TPSA113.81
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn orally-active prodrug of mecillinam, an extended-spectrum penicillin antibiotic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding7.5
  • Volume of distribution (VD)0.29 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPivmecillinam is hydrolyzed to mecillinam
  • Half life1~3 h
  • ExcretionRenal and biliary, mostly as mecillinam
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A