• Molecular NameValsartan
  • Synonymvalsartan
  • Weight435.528
  • Drugbank_IDDB00177
  • ACS_NO137862-53-4
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.9
  • pkaN/A
  • LogD (pH=7, predicted)-2.09
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.7
  • LogSw (predicted, AB/LogsW2.0)0.15
  • Sw (mg/ml) (predicted, ACD/Labs)0.03
  • No.of HBond Donors2
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds10
  • TPSA112.07
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn angiotensin II receptor antagonist (more commonly called an "ARB", which stands for angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor.
  • Absorption_value55.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability23.0
  • Protein binding95.0
  • Volume of distribution (VD)0.23 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life9.4 h
  • ExcretionRenal 30%, biliary 70%
  • Urinary Excretion29
  • Clerance0.49 ml/min/kg
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A