• Molecular NameMycophenolate_mofetil
  • SynonymMycophenylate mofetil
  • Weight433.501
  • Drugbank_IDDB00688
  • ACS_NON/A
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.97
  • pkaN/A
  • LogD (pH=7, predicted)3.52
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.17
  • LogSw (predicted, AB/LogsW2.0)0.05
  • Sw (mg/ml) (predicted, ACD/Labs)0.27
  • No.of HBond Donors1
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds10
  • TPSA94.53
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA immunosuppressant and prodrug of mycophenolic acid, used extensively in transplant medicine.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability0.0
  • Protein binding97.0
  • Volume of distribution (VD)3.6~4 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmMycophenolate mofetil (MM) is rapidly converted to the active mycophenolic acid (MPA) after IV and oral doses.
  • Half life<0.033 h
  • ExcretionN/A
  • Urinary Excretion1
  • Clerance120~163 ml/min/kg
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A