• Molecular NameBudesonide
  • Synonymbudesonide
  • Weight430.541
  • Drugbank_IDDB01222
  • ACS_NO51333-22-3
  • Show 2D model
  • LogP (experiment)3.145
  • LogP (predicted, AB/LogP v2.0)3.05
  • pkaN/A
  • LogD (pH=7, predicted)3.05
  • Solubility (experiment)insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-4.44
  • LogSw (predicted, AB/LogsW2.0)0.03
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors2
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds4
  • TPSA93.06
  • StatusFDA approved
  • AdministrationOral, Nasal, tracheal, rectal
  • PharmacologyA glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. Additionally, it is used for Crohn's disease (inflammatory bowel disease).
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability12.0
  • Protein binding88.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic CYP3A4
  • Half life2.0~3.6 h
  • ExcretionRenal, Faecal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySide effects include headache, respiratory infection, nausea, back pain, dyspepsia, dizziness, abdominal pain, flatulence, vomiting, fatigue
  • LD50 (rat)N/A
  • LD50 (mouse)N/A