• Molecular NameMebeverine
  • SynonymNA
  • Weight429.557
  • Drugbank_IDN/A
  • ACS_NO2753-45-9
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)4.69
  • pkaN/A
  • LogD (pH=7, predicted)2.57
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.38
  • LogSw (predicted, AB/LogsW2.0)0.02
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors0
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds14
  • TPSA57.23
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA musculotropic antispasmodic drug without atropic side-effects whose major therapeutic role is in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm secondary to organic disorder.
  • Absorption_value90.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=150 (ip)