• Molecular NameMelagatran
  • SynonymH 376/95; ximelagatran
  • Weight429.521
  • Drugbank_IDN/A
  • ACS_NO192939-46-1
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-0.7
  • pkaN/A
  • LogD (pH=7, predicted)-1.25
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.05
  • LogSw (predicted, AB/LogsW2.0)12.65
  • Sw (mg/ml) (predicted, ACD/Labs)0.06
  • No.of HBond Donors6
  • No.of HBond Acceptors9
  • No.of Rotatable Bonds9
  • TPSA148.61
  • StatusN/A
  • AdministrationN/A
  • PharmacologyAn anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability5.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmNone
  • Half lifeN/A
  • ExcretionRenal (80%)
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A