• Molecular NameDistigmine
  • SynonymNA
  • Weight416.522
  • Drugbank_IDN/A
  • ACS_NO15876-67-2
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-5.23
  • pkaN/A
  • LogD (pH=7, predicted)-5.23
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.07
  • LogSw (predicted, AB/LogsW2.0)133.08
  • Sw (mg/ml) (predicted, ACD/Labs)357.39
  • No.of HBond Donors0
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds11
  • TPSA66.84
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA parasympathomimetic.
  • Absorption_value8.0
  • Absorption (description)Poorly absorbed after oral administration.
  • Caco_2-6.8
  • Bioavailability8.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionLess than 5% of an oral dose is excreted in the urine in 24 h, compared to 50% of an IM dose.
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A