• Molecular NamePodofilox
  • SynonymPodophyllinic acid lactone
  • Weight414.41
  • Drugbank_IDDB01179
  • ACS_NO518-28-5
  • Show 3D model
  • LogP (experiment)2.01
  • LogP (predicted, AB/LogP v2.0)1.61
  • pkaN/A
  • LogD (pH=7, predicted)1.61
  • Solubility (experiment)0.1 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-4.26
  • LogSw (predicted, AB/LogsW2.0)0.18
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors1
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds4
  • TPSA92.68
  • StatusFDA approved
  • AdministrationTopical
  • PharmacologyIt is the main active antiwart component of podophyllin, an herbal extract of Podophyllum which used to be one of the main treatments for genital warts.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life1.0~4.5 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A