• Molecular NameClomifene
  • SynonymChlomaphene; Chloramifene; Chloramiphene; Cisclomiphene; Clomifene citrate; Clomifeno; clomiphene; Clomiphene Citrate; Clomiphene citrate (Z,E); Clomiphene dihydrogen citrate; Racemic clomiphene citrate; Zuclomiphene citrate
  • Weight405.969
  • Drugbank_IDDB00882
  • ACS_NO911-45-5
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)6.75
  • pkaN/A
  • LogD (pH=7, predicted)4.8
  • Solubility (experiment)Slightly soluble
  • LogS (predicted, ACD/Labs)(ph=7)-3.52
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors0
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds9
  • TPSA12.47
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA selective estrogen receptor modulator (SERM), increasing production of gonadotropins by inhibiting negative feedback on the hypothalamus.
  • Absorption_valueN/A
  • Absorption (description)Absorbed after oral administration
  • Caco_2N/A
  • Bioavailability90.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life5 days
  • ExcretionMainly renal, some biliary
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A