• Molecular NameOxacillin
  • SynonymOxacillin Sodium
  • Weight401.443
  • Drugbank_IDDB00713
  • ACS_NO66-79-5
  • Show 3D model
  • LogP (experiment)2.274
  • LogP (predicted, AB/LogP v2.0)2.05
  • pka2.78
  • LogD (pH=7, predicted)-1.92
  • Solubility (experiment)0.0139 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-0.05
  • LogSw (predicted, AB/LogsW2.0)0.77
  • Sw (mg/ml) (predicted, ACD/Labs)0.43
  • No.of HBond Donors2
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds4
  • TPSA138.04
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA narrow spectrum beta-lactam antibiotic of the penicillin class.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability33.0
  • Protein binding94.2
  • Volume of distribution (VD)0.24~0.42 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life20~30 min
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityAs for other penicillins, Oxacillin administration may result in immediate and delayed reactions to penicillin, neurotoxic, urogental, gastrointestinal, and metabolic reactions (rash, fever, eosinophilia, hematuria, proteinuria, renal insufficiency, colitis, agranulocytosis, neutropenia, bone marrow depression, nausea and vomiting).
  • LD50 (rat)N/A
  • LD50 (mouse)N/A