• Molecular NameCefalotin
  • SynonymCefalothin; Cefalotina [INN-Spanish]; Cefalotine [INN-French]; Cefalotinum [INN-Latin]; Cephalothin; Cephalothin Sodium; Cephalothinum; Cephalotin; CLS
  • Weight396.444
  • Drugbank_IDDB00456
  • ACS_NO153-61-7
  • Show 2D model
  • LogP (experiment)-0.41
  • LogP (predicted, AB/LogP v2.0)0.22
  • pka2.2
  • LogD (pH=7, predicted)-3.76
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.62
  • LogSw (predicted, AB/LogsW2.0)10.08
  • Sw (mg/ml) (predicted, ACD/Labs)0.16
  • No.of HBond Donors2
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds7
  • TPSA166.55
  • StatusFDA approved
  • AdministrationIV
  • PharmacologyA first-generation cephalosporin antibiotic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding73.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life0.5~1 h
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A