• Molecular NameMeclizine
  • SynonymNA
  • Weight390.958
  • Drugbank_IDDB00737
  • ACS_NO569-65-3
  • Show 3D model
  • LogP (experiment)5.9
  • LogP (predicted, AB/LogP v2.0)5.65
  • pka3.1, 6.2
  • LogD (pH=7, predicted)5.61
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.19
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors0
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA6.48
  • StatusFDA approved
  • AdministrationOral, Insufflation, Sublingual/Buccal.
  • PharmacologyAn antihistamine considered to be an antiemetic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life6 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A