• Molecular NameHetacillin
  • SynonymNA
  • Weight389.476
  • Drugbank_IDDB00739
  • ACS_NO3511-16-8
  • Show 3D model
  • LogP (experiment)0.95
  • LogP (predicted, AB/LogP v2.0)0.66
  • pkaN/A
  • LogD (pH=7, predicted)-2.04
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-0.7
  • LogSw (predicted, AB/LogsW2.0)11.5
  • Sw (mg/ml) (predicted, ACD/Labs)0.12
  • No.of HBond Donors2
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds3
  • TPSA115.25
  • StatusFDA approved; US withdrawn
  • AdministrationN/A
  • PharmacologyA beta-lactam. Hetacillin is a prodrug and it has no intrinsic antibacterial activity, but is converted by the body to ampicillin, which is active against a variety of organisms.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHydrolyzed to active ampicillin via esterases
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A