• Molecular NameCefprozil
  • SynonymCefprozil anhydrous; Cefprozilo [INN-Spanish]; Cefprozilum [INN-Latin]
  • Weight389.432
  • Drugbank_IDDB01150
  • ACS_NO92665-29-7
  • Show 3D model
  • LogP (experiment)0.209
  • LogP (predicted, AB/LogP v2.0)-0.96
  • pkaN/A
  • LogD (pH=7, predicted)-3.47
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.28
  • LogSw (predicted, AB/LogsW2.0)16.15
  • Sw (mg/ml) (predicted, ACD/Labs)0.68
  • No.of HBond Donors5
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds5
  • TPSA158.26
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA cephalosporin type antibiotic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability95.0
  • Protein binding40.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmCefprozil is eliminated primarily by the kidneys
  • Half life1.3 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySingle 5000 mg/kg oral doses of cefprozil caused no mortality or signs of toxicity in adult, weaning or neonatal rats, or adult mice. A single oral dose of 3000 mg/kg caused diarrhea and loss of appetite in cynomolgus monkeys, but no mortality.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A