• Molecular NameDepamide
  • SynonymNA
  • Weight143.23
  • Drugbank_IDN/A
  • ACS_NO2430-27-5
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.28
  • pkaN/A
  • LogD (pH=7, predicted)2.28
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.02
  • LogSw (predicted, AB/LogsW2.0)1.28
  • Sw (mg/ml) (predicted, ACD/Labs)1.36
  • No.of HBond Donors2
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA43.09
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA carboxamide derivative of valproic acid used in the treatment of epilepsy and some affective disorders.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability68.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmIt is rapidly metabolised (80%) to valproic acid (another anticonvulsant) but has anticonvulsant properties itself.
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A