• Molecular NameMeropenem
  • SynonymAntibiotic SM 7338; meropenem; Meropenem anhydrous; Meropenemum [INN-Latin]
  • Weight383.469
  • Drugbank_IDDB00760
  • ACS_NO119478-56-7
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-0.16
  • pkaN/A
  • LogD (pH=7, predicted)-2.66
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.86
  • LogSw (predicted, AB/LogsW2.0)61.27
  • Sw (mg/ml) (predicted, ACD/Labs)39.28
  • No.of HBond Donors3
  • No.of HBond Acceptors8
  • No.of Rotatable Bonds5
  • TPSA135.48
  • StatusFDA approved
  • AdministrationIV
  • PharmacologyAn ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia.
  • Absorption_value0.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability0.0
  • Protein binding2.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPrimarily excreted unchanged. There is one metabolite which is microbiologically inactive.
  • Half life1 h
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityIn mice and rats, large intravenous doses of meropenem (2200-4000 mg/kg) have been associated with ataxia, dyspnea, convulsions, and mortalities.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A