• Molecular NameEchothiophate Iodide
  • SynonymEchothiophate; Phospholine; Phospholine Iodide
  • Weight383.231
  • Drugbank_IDDB01057
  • ACS_NO736-03-4
  • Show 2D model
  • LogP (experiment)-2.25
  • LogP (predicted, AB/LogP v2.0)-4.17
  • pkaN/A
  • LogD (pH=7, predicted)-4.17
  • Solubility (experiment)Soluble
  • LogS (predicted, ACD/Labs)(ph=7)-0.05
  • LogSw (predicted, AB/LogsW2.0)61287.2
  • Sw (mg/ml) (predicted, ACD/Labs)230.82
  • No.of HBond Donors0
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds13
  • TPSA70.64
  • StatusFDA approved
  • AdministrationTopical (eye drops)
  • PharmacologyA parasympathomimetic and organophosphate. It is a cholinesterase inhibitor.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySide effects include blurred vision or change in near or distant vision and eye pain.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A