• Molecular NameChlorotrianisene
  • SynonymChloortrianisestrol; Chlorestrolo; Chlorotrianisenum [INN-Latin]; Chlorotrianisine; Chlorotrianizen; Chlortrianisen; Chlortrianisene; Chlortrianisenum; Chlortrianisestrol; Chlortrianisoestrolum; Chlortrianizen; Clorotrianiseno [INN-Spanish]; CTA
  • Weight380.871
  • Drugbank_IDDB00269
  • ACS_NO569-57-3
  • Show 3D model
  • LogP (experiment)6.7
  • LogP (predicted, AB/LogP v2.0)6.01
  • pkaN/A
  • LogD (pH=7, predicted)6.01
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-5.84
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors0
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds6
  • TPSA27.69
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA synthetic estrogen.
  • Absorption_valueN/A
  • Absorption (description)Absorption following oral administration is rapid.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding65.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmMetabolized principally in the liver, although the kidneys, gonads, and muscle tissues may be involved to some extent. The metabolic fate of the synthetic estrogens has not been fully elucidated.
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityAcute overdosage of large doses of oral contraceptives in chidren reportedly produces almost no toxicity except nausea and vomiting. Acute overdosage of estrogens may cause nausea, and withdrawal bleeding may occur in females.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A